Effect of thyroid hormone concentration on the transcriptional response underlying induced metamorphosis in the Mexican axolotl (Ambystoma).

TitleEffect of thyroid hormone concentration on the transcriptional response underlying induced metamorphosis in the Mexican axolotl (Ambystoma).
Publication TypeJournal Article
Year of Publication2008
JournalBMC genomics
Volume9
Pagination78
Date Published2008
Abstract

Thyroid hormones (TH) induce gene expression programs that orchestrate amphibian metamorphosis. In contrast to anurans, many salamanders do not undergo metamorphosis in nature. However, they can be induced to undergo metamorphosis via exposure to thyroxine (T4). We induced metamorphosis in juvenile Mexican axolotls (Ambystoma mexicanum) using 5 and 50 nM T4, collected epidermal tissue from the head at four time points (Days 0, 2, 12, 28), and used microarray analysis to quantify mRNA abundances.

URLhttps://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-9-78
DOI10.1186/1471-2164-9-78
Short TitleBMC Genomics
X
Enter your linkblue username.
Enter your linkblue password.
Secure Login

This login is SSL protected

Loading