HP1 complexes and heterochromatin assembly.

TitleHP1 complexes and heterochromatin assembly.
Publication TypeJournal Article
JournalCurrent topics in microbiology and immunology
Volume274
Pagination53-77
Date Published2003
ISSN0070-217X
Abstract

Since its discovery almost two decades ago, heterochromatin protein 1 (HP1) has emerged as a major player in the transcriptional regulation of both heterochromatic and euchromatic genes as well as the mechanics of chromosome segregation and the functional and structural organization of the interphase nucleus. Recent years have brought the identification of a myriad of HP1-interacting proteins. Each of these is discussed in relationship to its role in heterochromatin assembly and HP1 function. The breadth of functions represented by HP1-interacting proteins testifies to its pivotal role in the daily operations of the nucleus.

Short TitleCurr Top Microbiol Immunol
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