The early impact of genetics on our understanding of cell cycle regulation in Aspergillus nidulans.

TitleThe early impact of genetics on our understanding of cell cycle regulation in Aspergillus nidulans.
Publication TypeJournal Article
Year of Publication2004
JournalFungal genetics and biology : FG & B
Volume41
Issue4
Pagination401-10
Date Published2004 Apr
ISSN1087-1845
Abstract

The application of genetic analysis was crucial to the rapid progress that has been made in cell cycle research. Ron Morris, one of the first to apply genetics to cell cycle research, developed Aspergillus nidulans into an important model system for the analysis of many aspects of cell biology. Within the area of cell cycle research, Ron's laboratory is noted for development of novel cell biological and molecular genetic approaches as well as seminal insights regarding the regulation of mitosis, checkpoint regulation of the cell cycle, and the role of microtubule-based motors in chromosome segregation. In this special edition of FGB dedicated to Ron Morris, and in light of the recent progress in fungal genomics, we review the outstanding contributions his work made to our understanding of mitotic regulation. Indeed, his efforts have provided many mutants and experimental tools along with the conceptual framework for current and future studies of mitosis in A. nidulans.

URLhttp://linkinghub.elsevier.com/retrieve/pii/S108718450300207X
DOI10.1016/j.fgb.2003.11.009
Short TitleFungal Genet Biol
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