Sex differences in the neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal: reversal with an A1 receptor agonist or an NMDA receptor antagonist.

TitleSex differences in the neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal: reversal with an A1 receptor agonist or an NMDA receptor antagonist.
Publication TypeJournal Article
Year of Publication2008
JournalAlcoholism, clinical and experimental research
Volume32
Issue7
Pagination1260-70
ISSN0145-6008
Abstract

Neuronal adaptations that occur during chronic ethanol (EtOH) exposure have been observed to sensitize the brain to excitotoxic insult during withdrawal. The adenosine receptor system warrants further examination in this regard, as recent evidence has implicated adenosine receptor involvement in the behavioral effects of both EtOH exposure and withdrawal.

URLhttp://dx.doi.org/10.1111/j.1530-0277.2008.00681.x
DOI10.1111/j.1530-0277.2008.00681.x
Short TitleAlcohol Clin Exp Res
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