Mansi Sethi

Research Interests:
Neuroscience
Molecular Biology
Sleep and Circadian Rhythms
Bioinformatics
Biostatistics
data analysis
Cancer Biology
Education

2010 - 2016:      Ph.D., Biology, University of Kentucky  (Advisor: Dr. Bruce O’Hara) 

2011 - 2015:      Graduate Certificate in Applied Statistics University of Kentucky, Lexington, KY, USA

2003 - 2006:      B.S., Zoology (Honors) University of Delhi, New Delhi, Indiadidate, Biology 2010 - Present Ph.D. Can2016didate, B2010iology 2010 - Present Ph.D. Candidate, Biology 2010 - Present Ph.D. Candidate, Biology 201jfrff

Teaching Experience

Bio 302: Introduction to Neuroscience, Fall 2015 and Spring 2016

Bio 542: Histology (Lab), Spring 2015

Bio 304: Principles of Genetics (Lab), Spring 2014

Bio 155: Lab for Intro Biology I, Spring and Fall, 2013

Bio 151: Principles of Biology Lab I, Spring 2011 and 2012

Bio 153: Principles of Biology Lab II, Fall 2011 and 2012

Research projects

Data analysis for sleep-wake traits in knockout mice to identify potential genes influencing sleep, recorded with our non-invasive piezoelectric system.

Also, have done assessment of sleep wake behavior in:

      Alzheimer’s disease mouse model, and

     Type 2 diabetes and Alzheimer’s disease (db/AD mice) mouse model

Study of sleep wake dynamics in developing mice

Selected Publications:

Sethi M., Joshi S. S., Striz M., Cole N., Ryan J., Lhamon M.E., Agarwal A., Stacey J. Sukoff Rizzo S.J., Denegre J.M., Braun R.E., Fardo D.W., Donohue K.D., Chesler E.J., Svenson K.L., O'Hara B.F., Analysis of sleep traits in knockout mice from the large-scale KOMP2 population using a non-invasive, high-throughput piezoelectric system. BMC Bioinformatics 2015, 16(Suppl 15):P15. (Poster Abstract)

Sethi M., Joshi S. S., Webb R. L., Beckett T. L., Donohue K. D., Murphy M. P., O’Hara B. F., Duncan M. J., Increased fragmentation of sleep-wake cycles in the 5XFAD mouse model of Alzheimer’s disease. Neuroscience 2015, 290:80-89

Sethi M., Joshi S. S., Striz M., Cole N., Ryan J., Lhamon M.E., Agarwal A., Clark J., S.J., Denegre J.M., Braun R.E., Fardo D.W., Kumar V., Donohue K.D., Chesler E.J., Svenson K.L., O'Hara B.F., Phenotyping sleep-wake traits in knockout mice from the large-scale KOMP2 population to identify potential genes influencing sleep (in preparation)

Sethi M., Guerriero L., Wang C., Helman A. M., Macheda T., Murphy M.P., Stromberg A.J., Marilyn J. Duncan, O’Hara B.F. Altered sleep-wake behavior in a novel murine model of type 2 diabetes and Alzheimer’s disease (in preparation)

PubMed Publications*: 
  • M Sethi; SS Joshi; RL Webb; TL Beckett; KD Donohue; MP Murphy; BF O'Hara; MJ Duncan"Increased fragmentation of sleep-wake cycles in the 5XFAD mouse model of Alzheimer's disease."Neuroscience290.(2015):80-9.Details. Full text
* Publications are automatically pulled from pubmed.gov based on a user-specific query. Results may include incorrect citations. See: Tutorial on improving PubMed results.