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Beyond pairwise distances: neighbor-joining with phylogenetic diversity estimates.

Author
Abstract
:

The "neighbor-joining algorithm" is a recursive procedure for reconstructing trees that is based on a transformation of pairwise distances between leaves. We present a generalization of the neighbor-joining transformation, which uses estimates of phylogenetic diversity rather than pairwise distances in the tree. This leads to an improved neighbor-joining algorithm whose total running time is still polynomial in the number of taxa. On simulated data, the method outperforms other distance-based methods. We have implemented neighbor-joining for subtree weights in a program called MJOIN which is freely available under the Gnu Public License at http://bio.math.berkeley.edu/mjoin/.

Year of Publication
:
2006
Journal
:
Molecular biology and evolution
Volume
:
23
Issue
:
3
Number of Pages
:
491-8
ISSN Number
:
0737-4038
URL
:
https://academic.oup.com/mbe/article-lookup/doi/10.1093/molbev/msj059
DOI
:
10.1093/molbev/msj059
Short Title
:
Mol Biol Evol
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