A case of mixed connective tissue disease positive for proteinase 3 antineutrophil cytoplasmic antibody in a patient with slowly progressive type 1 diabetes mellitus and chronic thyroiditis .
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Abstract |
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A female in her sixties with slowly progressive type 1 diabetes mellitus (SPT1DM) and chronic thyroiditis was referred to our rheumatology department with swelling in her fingers. A prominent atherosclerotic lesion was revealed upon brain magnetic resonance imaging, and she was found to have mixed connective tissue disease (MCTD) positive for proteinase 3 (PR3)-antineutrophil cytoplasmic antibody (ANCA). This rare case of MCTD accompanying SPT1DM and PR3-ANCA suggested that a synergy between MCTD and PR3-ANCA triggers atherosclerosis. |
Year of Publication |
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0
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Journal |
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Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology
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Volume |
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40
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Issue |
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6
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Number of Pages |
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467-470
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Date Published |
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2017
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ISSN Number |
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0911-4300
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URL |
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https://dx.doi.org/10.2177/jsci.40.467
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DOI |
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10.2177/jsci.40.467
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Short Title |
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Nihon Rinsho Meneki Gakkai Kaishi
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