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Evaluation of fluorine-18-BPA-fructose for boron neutron capture treatment planning.

Author
Abstract
:

Boron neutron capture therapy (BNCT) using 4-[10B]boronophenylalanine-fructose (BPA-Fr) is in Phase II clinical trials to validate BNCT as a treatment for glioblastoma multiforme and melanoma. Successful BNCT depends on knowledge of the distribution of boron-containing agents in both tumor and normal tissue as currently determined by chemical confirmation of boron deposition in surgically removed malignant tissue before BNCT.

Year of Publication
:
1997
Journal
:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Volume
:
38
Issue
:
11
Number of Pages
:
1762-7
ISSN Number
:
0161-5505
URL
:
http://jnm.snmjournals.org/cgi/pmidlookup?view=long&pmid=9374349
Short Title
:
J Nucl Med
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