Skip to main content

Studies on the development of ¹⁶⁹Yb-brachytherapy seeds: New generation brachytherapy sources for the management of cancer.

Author
Abstract
:

This paper describes development of (169)Yb-seeds by encapsulating 0.6-0.65 mm (ϕ) sized (169)Yb2O3 microspheres in titanium capsules. Microspheres synthesized by a sol-gel route were characterized by XRD, SEM/EDS and ICP-AES. Optimization of neutron irradiation was accomplished and (169)Yb-seeds up to 74 MBq of (169)Yb could be produced from natural Yb2O3 microspheres, which have the potential for use in prostate brachytherapy. A protocol to prepare (169)Yb-brachytherapy sources (2.96-3.7 TBq of (169)Yb) with the use of enriched targets was also formulated.

Year of Publication
:
2015
Journal
:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
Volume
:
101
Number of Pages
:
75-82
ISSN Number
:
0969-8043
URL
:
https://linkinghub.elsevier.com/retrieve/pii/S0969-8043(15)00098-6
DOI
:
10.1016/j.apradiso.2015.03.020
Short Title
:
Appl Radiat Isot
Download citation