Negative affect increases in the hours prior to binge eating (BE), suggesting individuals may use BE to attempt to alleviate experiences of aversive self-awareness, such as shame and guilt. Guilt involves feeling bad about ones behavior and may elicit reparative actions; shame involves feeling bad about oneself and is generally associated with maladaptive behavior. Distinguishing how shame and guilt differentially relate to specific eating disorder (ED) behaviors may inform our understanding of emotional antecedents of ED behaviors and lead to refined treatment and prevention targets. We aimed to distinguish shame and guilt as they relate to BE and self-induced vomiting (SIV). We hypothesized that: (a) shame-proneness and state shame would be uniquely associated with BE, as BE may be used to escape from experiences of shame, and (b) guilt-proneness and state guilt would be positively associated with SIV among individuals who binge eat, as SIV may be used as a reparative action for BE. Participants (N = 347) completed self-report measures assessing guilt, shame, and ED behaviors. Shame-proneness and state shame were uniquely associated with BE and the urge to binge eat, while guilt-proneness and state guilt were not. Contrary to our hypothesis, guilt-proneness and state guilt were not associated with SIV among those who binge eat or endorsed urges to binge eat. These findings suggest that shame and guilt are differentially related to ED behaviors and identify shame specifically as an emotion that may elicit BE. Future research is needed to identify temporal relations between shame and ED behaviors.