Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles.
| Author | |
|---|---|
| Abstract |
:
Intellectual disability, accelerated aging, and early-onset Alzheimer-like neurodegeneration are key brain pathological features of Down syndrome (DS). Although growing research aims at the identification of molecular pathways underlying the aging trajectory of DS population, data on infants and adolescents with DS are missing. |
| Year of Publication |
:
2022
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| Journal |
:
Alzheimer's & dementia : the journal of the Alzheimer's Association
|
| Volume |
:
18
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| Issue |
:
8
|
| Number of Pages |
:
1498-1510
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| ISSN Number |
:
1552-5260
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| URL |
:
https://doi.org/10.1002/alz.12499
|
| DOI |
:
10.1002/alz.12499
|
| Short Title |
:
Alzheimers Dement
|
| Download citation |
