Skip to main content

Proton Pump Inhibitors Increase the Susceptibility of Mice to Oral Infection with Enteropathogenic Bacteria.

Author
Abstract
:

Proton pump inhibitors (PPIs) are among the most frequently prescribed medications. Side effects including an increased risk of intestinal infections have been reported. It is assumed that PPIs can increase susceptibility to enteropathogens; however, the underlying mechanisms are unknown. Here in this study, we explored whether Lansoprazole (Laz), one of the PPIs, increases the susceptibility to enteropathogens, and further investigated the mechanism of it.

Year of Publication
:
2018
Journal
:
Digestive diseases and sciences
Date Published
:
2018
ISSN Number
:
0163-2116
DOI
:
10.1007/s10620-017-4905-3
Short Title
:
Dig Dis Sci
Download citation