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Mark A. Prendergast

Research Interests:
Neuroscience Teaching
Alcohol Dependence
Amphetamine Abuse
Stress Hormones
Brain Injury
Research

My laboratory's research efforts are focused on examining biochemical mechanisms involved with the development of alcohol and drug dependence. In addition, we study novel drug targets, such as stress hormone receptors systems, that might be targeted in the treatment of dependence.

In studying these topics, my laboratory employs a broad range of neurochemical and behavioral techniques, including cell culture of brain tissue, in vivo rodent studies, ELISA, Western blot analysis and immunohistochemistry.

 

for more information, please visit: https://www.facebook.com/prendergastlabuky/?ref=bookmarks

 

 

Graduate Training
Ph.D. Univ. of Nebraska, 1994
PubMed Publications*: 
  • CS Bailey; JE Jagielo-Miller; PS Keller; EP Glaser; AL Wilcox; MA Prendergast"Ethanol sustains phosphorylated tau protein in the cultured neonatal rat hippocampus: Implications for fetal alcohol spectrum disorders."Alcohol (Fayetteville, N.Y.)103.(2022):45-54.Details. Full text
  • SE Eaton; JE Jagielo-Miller; MA Prendergast; CK Akins"Sex differences in alcohol dehydrogenase levels (ADH) and blood ethanol concentration (BEC) in Japanese quail."Poultry science101.5(2022):101790.Details. Full text
  • BA Rice; MA Saunders; JE Jagielo-Miller; MA Prendergast; CK Akins"Repeated subcutaneous administration of PT150 has dose-dependent effects on sign tracking in male Japanese quail."Experimental and clinical psychopharmacology27.6(2019):515-521.Details. Full text
  • SE Maggio; MA Saunders; K Nixon; MA Prendergast; G Zheng; PA Crooks; LP Dwoskin; RL Bell; MT Bardo"An improved model of ethanol and nicotine co-use in female P rats: Effects of naltrexone, varenicline, and the selective nicotinic α6β2* antagonist r-bPiDI."Drug and alcohol dependence193.(2018):154-161.Details. Full text
  • BA Rice; SE Eaton; MA Prendergast; CK Akins"A glucocorticoid receptor antagonist reduces sign-tracking behavior in male Japanese quail."Experimental and clinical psychopharmacology26.4(2018):329-334.Details. Full text
  • AR Reynolds; MA Saunders; JN Berry; LJ Sharrett-Field; S Winchester; MA Prendergast"Broad-spectrum protein kinase inhibition by the staurosporine analog KT-5720 reverses ethanol withdrawal-associated loss of NeuN/Fox-3."Alcohol (Fayetteville, N.Y.)64.(2017):37-43.Details. Full text
  • KA Shaaban; MA Saunders; Y Zhang; T Tran; SI Elshahawi; LV Ponomareva; X Wang; J Zhang; GC Copley; M Sunkara; MK Kharel; AJ Morris; JC Hower; MS Tremblay; MA Prendergast; JS Thorson"Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6."Journal of natural products80.1(2017):2-11.Details. Full text
  • J Zhang; RR Hughes; MA Saunders; SI Elshahawi; LV Ponomareva; Y Zhang; Winchester SR; SA Scott; M Sunkara; AJ Morris; MA Prendergast; KA Shaaban; JS Thorson"Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning."Journal of natural products80.1(2017):12-18.Details. Full text
  • AR Reynolds; MA Saunders; MA Prendergast"Ethanol Stimulates Endoplasmic Reticulum Inositol Triphosphate and Sigma Receptors to Promote Withdrawal-Associated Loss of Neuron-Specific Nuclear Protein/Fox-3."Alcoholism, clinical and experimental research40.7(2016):1454-61.Details. Full text
  • CE Van Skike; SE Maggio; AR Reynolds; EM Casey; MT Bardo; LP Dwoskin; MA Prendergast; K Nixon"Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse."Progress in neuro-psychopharmacology & biological psychiatry65.(2016):269-87.Details. Full text
  • AR Reynolds; JN Berry; L Sharrett-Field; MA Prendergast"Ethanol withdrawal is required to produce persisting N-methyl-D-aspartate receptor-dependent hippocampal cytotoxicity during chronic intermittent ethanol exposure."Alcohol (Fayetteville, N.Y.)49.3(2015):219-27.Details. Full text
  • X Wang; AR Reynolds; SI Elshahawi; KA Shaaban; LV Ponomareva; MA Saunders; IS Elgumati; Y Zhang; GC Copley; JC Hower; M Sunkara; AJ Morris; MK Kharel; SG Van Lanen; MA Prendergast; JS Thorson"Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8."Organic letters17.11(2015):2796-9.Details. Full text
  • AR Reynolds; MA Saunders; HW Brewton; Winchester SR; IS Elgumati; MA Prendergast"Acute oral administration of the novel, competitive and selective glucocorticoid receptor antagonist ORG 34517 reduces the severity of ethanol withdrawal and related hypothalamic-pituitary-adrenal axis activation."Drug and alcohol dependence154.(2015):100-4.Details. Full text
  • AR Reynolds; LA Williams; MA Saunders; MA Prendergast"Group 1 mGlu-family proteins promote neuroadaptation to ethanol and withdrawal-associated hippocampal damage."Drug and alcohol dependence156.(2015):213-220.Details. Full text
  • X Wang; AR Reynolds; SI Elshahawi; KA Shaaban; LV Ponomareva; MA Saunders; IS Elgumati; Y Zhang; GC Copley; JC Hower; M Sunkara; AJ Morris; MK Kharel; SG Van Lanen; MA Prendergast; JS Thorson"Correction to "Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8"."Organic letters17.21(2015):5515.Details. Full text
  • L Sharrett-Field; TR Butler; JN Berry; AR Reynolds; MA Prendergast"Mifepristone pretreatment reduces ethanol withdrawal severity in vivo."Alcoholism, clinical and experimental research37.8(2013):1417-23.Details. Full text
  • L Sharrett-Field; TR Butler; AR Reynolds; JN Berry; MA Prendergast"Sex differences in neuroadaptation to alcohol and withdrawal neurotoxicity."Pflugers Archiv : European journal of physiology465.5(2013):643-54.Details. Full text
  • JA Rumbaugh; M Bachani; W Li; TR Butler; KJ Smith; MA Bianchet; T Wang; MA Prendergast; N Sacktor; A Nath"HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors."Neurobiology of disease49.(2013):169-76.Details. Full text
  • TR Butler; JN Berry; LJ Sharrett-Field; Pauly JR; MA Prendergast"Long-term ethanol and corticosterone co-exposure sensitize the hippocampal ca1 region pyramidal cells to insult during ethanol withdrawal in an NMDA GluN2B subunit-dependent manner."Alcoholism, clinical and experimental research37.12(2013):2066-73.Details. Full text
  • KJ Smith; TR Butler; MA Prendergast"Ethanol impairs microtubule formation via interactions at a microtubule associated protein-sensitive site."Alcohol (Fayetteville, N.Y.)47.7(2013):539-43.Details. Full text
  • TR Butler; MA Prendergast"Neuroadaptations in adenosine receptor signaling following long-term ethanol exposure and withdrawal."Alcoholism, clinical and experimental research36.1(2012):4-13.Details. Full text
  • DO Thompson; MA Prendergast; LW Shockley"Traumatic pneumothorax with air mimicking lung markings."The Journal of emergency medicine43.6(2012):e463-4.Details. Full text
  • MA Prendergast; PJ Mulholland"Glucocorticoid and polyamine interactions in the plasticity of glutamatergic synapses that contribute to ethanol-associated dependence and neuronal injury."Addiction biology17.2(2012):209-23.Details. Full text
  • S Rahman; MA Prendergast"Cholinergic receptor system as a target for treating alcohol abuse and dependence."Recent patents on CNS drug discovery7.2(2012):145-50.Details.
  • JN Berry; LJ Sharrett-Field; TR Butler; MA Prendergast"Temporal dependence of cysteine protease activation following excitotoxic hippocampal injury."Neuroscience222.(2012):147-58.Details. Full text
  • TR Butler; KJ Smith; RL Self; BB Braden; MA Prendergast"Neurodegenerative effects of recombinant HIV-1 Tat(1-86) are associated with inhibition of microtubule formation and oxidative stress-related reductions in microtubule-associated protein-2(a,b)."Neurochemical research36.5(2011):819-28.Details. Full text
  • AK Rose; SG Shaw; MA Prendergast; HJ Little"The importance of glucocorticoids in alcohol dependence and neurotoxicity."Alcoholism, clinical and experimental research34.12(2010):2011-8.Details. Full text
  • KJ Smith; TR Butler; MA Prendergast"Inhibition of sigma-1 receptor reduces N-methyl-D-aspartate induced neuronal injury in methamphetamine-exposed and -naive hippocampi."Neuroscience letters481.3(2010):144-8.Details. Full text
  • TR Butler; RL Self; KJ Smith; LJ Sharrett-Field; JN Berry; JM Littleton; Pauly JR; PJ Mulholland; MA Prendergast"Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors."Neuroscience165.2(2010):525-34.Details. Full text
  • RL Self; KJ Smith; TR Butler; Pauly JR; MA Prendergast"Intra-cornu ammonis 1 administration of the human immunodeficiency virus-1 protein trans-activator of transcription exacerbates the ethanol withdrawal syndrome in rodents and activates N-methyl-D-aspartate glutamate receptors to produce persisting..."Neuroscience163.3(2009):868-76.Details. Full text
  • C Jacquot; AP Croft; MA Prendergast; P Mulholland; SG Shaw; HJ Little"Effects of the glucocorticoid antagonist, mifepristone, on the consequences of withdrawal from long term alcohol consumption."Alcoholism, clinical and experimental research32.12(2008):2107-16.Details. Full text
  • TR Butler; KJ Smith; RL Self; BB Braden; MA Prendergast"Sex differences in the neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal: reversal with an A1 receptor agonist or an NMDA receptor antagonist."Alcoholism, clinical and experimental research32.7(2008):1260-70.Details. Full text
  • S Barron; PJ Mulholland; JM Littleton; MA Prendergast"Age and gender differences in response to neonatal ethanol withdrawal and polyamine challenge in organotypic hippocampal cultures."Alcoholism, clinical and experimental research32.6(2008):929-36.Details. Full text
  • KJ Smith; TR Butler; RL Self; BB Braden; MA Prendergast"Potentiation of N-methyl-D-aspartate receptor-mediated neuronal injury during methamphetamine withdrawal in vitro requires co-activation of IP3 receptors."Brain research1187.(2008):67-73.Details. Full text
  • MA Prendergast; HJ Little"Adolescence, glucocorticoids and alcohol."Pharmacology, biochemistry, and behavior86.2(2007):234-45.Details. Full text
  • DA Gearhart; DW Sickles; JJ Buccafusco; MA Prendergast; Terry AV Jr"Chlorpyrifos, chlorpyrifos-oxon, and diisopropylfluorophosphate inhibit kinesin-dependent microtubule motility."Toxicology and applied pharmacology218.1(2007):20-9.Details. Full text
  • MA Prendergast; RL Self; KJ Smith; L Ghayoumi; MM Mullins; TR Butler; JJ Buccafusco; DA Gearhart; Terry AV Jr"Microtubule-associated targets in chlorpyrifos oxon hippocampal neurotoxicity."Neuroscience146.1(2007):330-9.Details. Full text
  • JJ Buccafusco; JC Powers; MA Hernandez; MA Prendergast; AV Terry; RR Jonnala"MHP-133, a drug with multiple CNS targets: potential for neuroprotection and enhanced cognition."Neurochemical research32.7(2007):1224-37.Details. Full text
  • KJ Smith; RL Self; TR Butler; MM Mullins; L Ghayoumi; RC Holley; JM Littleton; MA Prendergast"Methamphetamine exposure antagonizes N-methyl-D-aspartate receptor-mediated neurotoxicity in organotypic hippocampal slice cultures."Brain research1157.(2007):74-80.Details. Full text
  • Terry AV Jr; DA Gearhart; Beck WD Jr; JN Truan; ML Middlemore; LN Williamson; MG Bartlett; MA Prendergast; DW Sickles; JJ Buccafusco"Chronic, intermittent exposure to chlorpyrifos in rats: protracted effects on axonal transport, neurotrophin receptors, cholinergic markers, and information processing."The Journal of pharmacology and experimental therapeutics322.3(2007):1117-28.Details. Full text
  • PJ Mulholland; RL Self; AK Hensley; HJ Little; JM Littleton; MA Prendergast"A 24 h corticosterone exposure exacerbates excitotoxic insult in rat hippocampal slice cultures independently of glucocorticoid receptor activation or protein synthesis."Brain research1082.1(2006):165-72.Details. Full text
  • Wilkins LH Jr; MA Prendergast; J Blanchard; RC Holley; ER Chambers; JM Littleton"Potential value of changes in cell markers in organotypic hippocampal cultures associated with chronic EtOH exposure and withdrawal: comparison with NMDA-induced changes."Alcoholism, clinical and experimental research30.10(2006):1768-80.Details. Full text
  • RL Self; KJ Smith; PJ Mulholland; MA Prendergast"Ethanol exposure and withdrawal sensitizes the rat hippocampal CA1 pyramidal cell region to beta-amyloid (25-35)-induced cytotoxicity: NMDA receptor involvement."Alcoholism, clinical and experimental research29.11(2005):2063-9.Details.
  • PJ Mulholland; RL Self; BR Harris; HJ Little; JM Littleton; MA Prendergast"Corticosterone increases damage and cytosolic calcium accumulation associated with ethanol withdrawal in rat hippocampal slice cultures."Alcoholism, clinical and experimental research29.5(2005):871-81.Details.
  • PJ Mulholland; RL Self; BR Harris; JM Littleton; MA Prendergast"Choline exposure reduces potentiation of N-methyl-D-aspartate toxicity by corticosterone in the developing hippocampus."Brain research. Developmental brain research153.2(2004):203-11.Details. Full text
  • RL Self; PJ Mulholland; A Nath; BR Harris; MA Prendergast"The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site."Brain research995.1(2004):39-45.Details. Full text
  • RL Self; PJ Mulholland; BR Harris; A Nath; MA Prendergast"Cytotoxic effects of exposure to the human immunodeficiency virus type 1 protein Tat in the hippocampus are enhanced by prior ethanol treatment."Alcoholism, clinical and experimental research28.12(2004):1916-24.Details.
  • DA Gibson; BR Harris; MA Prendergast; Hart SR; 2nd JA; RC Holley; NW Pedigo; JM Littleton"Polyamines contribute to ethanol withdrawal-induced neurotoxicity in rat hippocampal slice cultures through interactions with the NMDA receptor."Alcoholism, clinical and experimental research27.7(2003):1099-106.Details.
  • TH Kelly; WW Stoops; AS Perry; MA Prendergast; CR Rush"Clinical neuropharmacology of drugs of abuse: a comparison of drug-discrimination and subject-report measures."Behavioral and cognitive neuroscience reviews2.4(2003):227-60.Details.
  • BR Harris; DA Gibson; MA Prendergast; JA Blanchard; RC Holley; Hart SR; RL Scotland; TC Foster; NW Pedigo; JM Littleton"The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors."Alcoholism, clinical and experimental research27.11(2003):1724-35.Details.
  • JN Bain; MA Prendergast; Terry AV Jr; SP Arneric; MA Smith; JJ Buccafusco"Enhanced attention in rhesus monkeys as a common factor for the cognitive effects of drugs with abuse potential."Psychopharmacology169.2(2003):150-60.Details. Full text
  • PJ Mulholland; MA Prendergast"Transection of intrinsic polysynaptic pathways reduces N-methyl-D-aspartate neurotoxicity in hippocampal slice cultures."Neuroscience research46.3(2003):369-76.Details. Full text
  • Terry AV Jr; JD Stone; JJ Buccafusco; DW Sickles; A Sood; MA Prendergast"Repeated exposures to subthreshold doses of chlorpyrifos in rats: hippocampal damage, impaired axonal transport, and deficits in spatial learning."The Journal of pharmacology and experimental therapeutics305.1(2003):375-84.Details. Full text
  • S Mayer; B Harris; DA Gibson; J Blanchard; MA Prendergast; RC Holley; J Littleton"Acamprosate has no effect on NMDA-induced toxicity but reduces toxicity induced by spermidine or by changing the medium in organotypic hippocampal slice cultures from rat."Alcoholism, clinical and experimental research26.5(2002):655-62.Details.
  • PJ Mulholland; MA Prendergast"Post-insult exposure to (+/-) kavain potentiates N-methyl-D-aspartate toxicity in the developing hippocampus."Brain research945.1(2002):106-13.Details. Full text
  • MA Prendergast; DP Yells; SE Balogh; Paige SR; SE Hendricks"Fluoxetine differentially suppresses sucrose solution consumption in free-fed and food-deprived rats--reversal by amantadine."Medical science monitor : international medical journal of experimental and clinical research8.10(2002):BR385-90.Details. Full text
  • S Mayer; BR Harris; DA Gibson; JA Blanchard; MA Prendergast; RC Holley; J Littleton"Acamprosate, MK-801, and ifenprodil inhibit neurotoxicity and calcium entry induced by ethanol withdrawal in organotypic slice cultures from neonatal rat hippocampus."Alcoholism, clinical and experimental research26.10(2002):1468-78.Details.
  • MA Prendergast; DT Rogers; PJ Mulholland; JM Littleton; Wilkins LH Jr; RL Self; A Nath"Neurotoxic effects of the human immunodeficiency virus type-1 transcription factor Tat require function of a polyamine sensitive-site on the N-methyl-D-aspartate receptor."Brain research954.2(2002):300-7.Details. Full text
  • BR Harris; MA Prendergast; DA Gibson; DT Rogers; JA Blanchard; RC Holley; MC Fu; Hart SR; NW Pedigo; JM Littleton"Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors."Alcoholism, clinical and experimental research26.12(2002):1779-93.Details.
  • MA Prendergast; BR Harris; 2nd JA; S Mayer; DA Gibson; JM Littleton"In vitro effects of ethanol withdrawal and spermidine on viability of hippocampus from male and female rat."Alcoholism, clinical and experimental research24.12(2000):1855-61.Details.
  • MA Prendergast; BR Harris; S Mayer; JM Littleton"Chronic, but not acute, nicotine exposure attenuates ethanol withdrawal-induced hippocampal damage in vitro."Alcoholism, clinical and experimental research24.10(2000):1583-92.Details.
  • JD Stone; Terry AV Jr; Pauly JR; MA Prendergast; JJ Buccafusco"Protractive effects of chronic treatment with an acutely sub-toxic regimen of diisopropylflurophosphate on the expression of cholinergic receptor densities in rats."Brain research882.1-2(2000):9-18.Details. Full text
  • MA Prendergast; WJ Jackson; Terry AV Jr; MW Decker; SP Arneric; JJ Buccafusco"Central nicotinic receptor agonists ABT-418, ABT-089, and (-)-nicotine reduce distractibility in adult monkeys."Psychopharmacology136.1(1998):50-8.Details. Full text
  • MA Prendergast; JJ Buccafusco"(-)-Nicotine increases mRNA encoding G3PDH and the vesicular acetylcholine transporter in vivo."Neuroreport9.7(1998):1385-9.Details. Full text
  • MA Prendergast; WJ Jackson; Terry AV Jr; NJ Kille; SP Arneric; MW Decker; JJ Buccafusco"Age-related differences in distractibility and response to methylphenidate in monkeys."Cerebral cortex (New York, N.Y. : 1991)8.2(1998):164-72.Details. Full text
  • Terry AV Jr; JJ Buccafusco; WJ Jackson; MA Prendergast; DJ Fontana; EH Wong; DW Bonhaus; P Weller; RM Eglen"Enhanced delayed matching performance in younger and older macaques administered the 5-HT4 receptor agonist, RS 17017."Psychopharmacology135.4(1998):407-15.Details. Full text
  • MA Prendergast; Terry AV Jr; WJ Jackson; KC Marsh; MW Decker; SP Arneric; JJ Buccafusco"Improvement in accuracy of delayed recall in aged and non-aged, mature monkeys after intramuscular or transdermal administration of the CNS nicotinic receptor agonist ABT-418."Psychopharmacology130.3(1997):276-84.Details. Full text
  • MW Decker; AW Bannon; P Curzon; KL Gunther; JD Brioni; MW Holladay; NH Lin; Y Li; JF Daanen; JJ Buccafusco; MA Prendergast; WJ Jackson; SP Arneric"ABT-089 2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride : II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys."The Journal of pharmacology and experimental therapeutics283.1(1997):247-58.Details. Full text
  • MA Prendergast; Terry AV Jr; WJ Jackson; JJ Buccafusco"Nitric oxide synthase inhibition impairs delayed recall in mature monkeys."Pharmacology, biochemistry, and behavior56.1(1997):81-7.Details. Full text
  • MA Prendergast; Terry AV Jr; JJ Buccafusco"Chronic, low-level exposure to diisopropylfluorophosphate causes protracted impairment of spatial navigation learning."Psychopharmacology129.2(1997):183-91.Details. Full text
  • NH Lin; DE Gunn; KB Ryther; DS Garvey; DL Donnelly-Roberts; MW Decker; JD Brioni; MJ Buckley; AD Rodrigues; KG Marsh; DJ Anderson; JJ Buccafusco; MA Prendergast; JP Sullivan; M Williams; SP Arneric; MW Holladay"Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties."Journal of medicinal chemistry40.3(1997):385-90.Details. Full text
  • MA Prendergast; SE Hendricks; DP Yells; S Balogh"Conditioned taste aversion induced by fluoxetine."Physiology & behavior60.1(1996):311-5.Details. Full text
  • Terry AV Jr; JJ Buccafusco; MA Prendergast; WJ Jackson; DL Fontana; EH Wong; RL Whiting; RM Eglen"The 5-HT3 receptor antagonist, RS-56812, enhances delayed matching performance in monkeys."Neuroreport8.1(1996):49-54.Details. Full text
  • DP Yells; MA Prendergast; SE Hendricks; ME Miller"Monoaminergic influences on temporal patterning of sexual behavior in male rats."Physiology & behavior58.5(1995):847-52.Details. Full text
  • DP Yells; MA Prendergast; SE Hendricks; M Nakamura"Fluoxetine-induced inhibition of male rat copulatory behavior: modification by lesions of the nucleus paragigantocellularis."Pharmacology, biochemistry, and behavior49.1(1994):121-7.Details. Full text
  • DP Yells; SE Hendricks; MA Prendergast"Lesions of the nucleus paragigantocellularis: effects on mating behavior in male rats."Brain research596.1-2(1992):73-9.Details. Full text
  • MS Clarke; MA Prendergast; Terry AV Jr"Plasma membrane ordering agent pluronic F-68 (PF-68) reduces neurotransmitter uptake and release and produces learning and memory deficits in rats."Learning & memory (Cold Spring Harbor, N.Y.)6.6(1969):634-49.Details.
  • TR Butler; KJ Smith; JN Berry; LJ Sharrett-Field; MA Prendergast"Sex differences in caffeine neurotoxicity following chronic ethanol exposure and withdrawal."Alcohol and alcoholism (Oxford, Oxfordshire)44.6(1969):567-74.Details. Full text
  • LL Devaud; MA Prendergast"Introduction to the special issue of Alcohol and Alcoholism on sex/gender differences in responses to alcohol."Alcohol and alcoholism (Oxford, Oxfordshire)44.6(1969):533-4.Details. Full text
  • MA Prendergast"Do women possess a unique susceptibility to the neurotoxic effects of alcohol?"Journal of the American Medical Women's Association (1972)59.3(1969):225-7.Details.
  • PJ Mulholland; BR Harris; LH Wilkins; RL Self; JA Blanchard; RC Holley; JM Littleton; MA Prendergast"Opposing effects of ethanol and nicotine on hippocampal calbindin-D28k expression."Alcohol (Fayetteville, N.Y.)31.1-2(1969):1-10.Details. Full text
  • RA Hart; MA Prendergast; WG Roberts; GM Nesbit; SL Barnwell"Proximal junctional acute collapse cranial to multi-level lumbar fusion: a cost analysis of prophylactic vertebral augmentation."The spine journal : official journal of the North American Spine Society8.6(1969):875-81.Details. Full text
  • MA Prendergast; BR Harris; S Mayer; RC Holley; Pauly JR; JM Littleton"Nicotine exposure reduces N-methyl-D-aspartate toxicity in the hippocampus: relation to distribution of the alpha7 nicotinic acetylcholine receptor subunit."Medical science monitor : international medical journal of experimental and clinical research7.6(1969):1153-60.Details.
  • CA Briggs; DJ Anderson; JD Brioni; JJ Buccafusco; MJ Buckley; JE Campbell; MW Decker; D Donnelly-Roberts; RL Elliott; M Gopalakrishnan; MW Holladay; YH Hui; WJ Jackson; DJ Kim; KC Marsh; A O'Neill; MA Prendergast; KB Ryther; JP Sullivan; SP Arneric"Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo."Pharmacology, biochemistry, and behavior57.1-2(1969):231-41.Details. Full text
  • MA Prendergast; Terry AV Jr; JJ Buccafusco"Effects of chronic, low-level organophosphate exposure on delayed recall, discrimination, and spatial learning in monkeys and rats."Neurotoxicology and teratology20.2(1969):115-22.Details. Full text
  • MA Prendergast; JJ Buccafusco; Terry AV Jr"Nitric oxide synthase inhibition impairs spatial navigation learning and induces conditioned taste aversion."Pharmacology, biochemistry, and behavior57.1-2(1969):347-52.Details. Full text
  • MA Prendergast; BR Harris; S Mayer; RC Holley; KF Hauser; JM Littleton"Chronic nicotine exposure reduces N-methyl-D-aspartate receptor-mediated damage in the hippocampus without altering calcium accumulation or extrusion: evidence of calbindin-D28K overexpression."Neuroscience102.1(0):75-85.Details. Full text
  • RA Hart; MA Prendergast"Spine surgery for lumbar degenerative disease in elderly and osteoporotic patients."Instructional course lectures56.(0):257-72.Details.
  • MA Prendergast; BR Harris; PJ Mullholland; 2nd JA; DA Gibson; RC Holley; JM Littleton"Hippocampal CA1 region neurodegeneration produced by ethanol withdrawal requires activation of intrinsic polysynaptic hippocampal pathways and function of N-methyl-D-aspartate receptors."Neuroscience124.4(0):869-77.Details. Full text
  • PJ Mulholland; RL Self; BR Harris; JM Littleton; MA Prendergast"(-)-nicotine ameliorates corticosterone's potentiation of N-methyl-d-aspartate receptor-mediated cornu ammonis 1 toxicity."Neuroscience125.3(0):671-82.Details. Full text
  • PJ Mulholland; RL Self; TD Stepanyan; HJ Little; JM Littleton; MA Prendergast"Thiamine deficiency in the pathogenesis of chronic ethanol-associated cerebellar damage in vitro."Neuroscience135.4(0):1129-39.Details. Full text
  • PJ Mulholland; TD Stepanyan; RL Self; AK Hensley; BR Harris; A Kowalski; JM Littleton; MA Prendergast"Corticosterone and dexamethasone potentiate cytotoxicity associated with oxygen-glucose deprivation in organotypic cerebellar slice cultures."Neuroscience136.1(0):259-67.Details. Full text
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